| Autor: |
Nakamura, Mitsuhiro, Murakami, Ryusuke, Abiko, Kaoru, Miyamoto, Taito, Kitawaki, Yoshimi, Yamaguchi, Ken, Horie, Akihito, Hamanishi, Junzo, Kodoh, Eiji, Baba, Tsukasa, Kido, Aki, Minamiguchi, Sachiko, Matsumura, Noriomi, Mandai, Masaki |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Case Reports in Obstetrics and Gynecology. |
| ISSN: |
2090-6684 |
| DOI: |
10.1155/2020/8973262 |
| Popis: |
Low-grade endometrial stromal sarcoma (LG-ESS) is a rare malignant disease and demonstrates various patterns in preoperative imaging. Therefore, accurate diagnosis is important. Given its unique form, we report a case of LG-ESS with a nodule-in-nodule appearance on preoperative imaging. A 41-year-old woman was referred to our department for further examination of a 45 mm diameter uterine corpus mass. Preoperative magnetic resonance imaging (MRI) revealed several small nodules within a larger nodule. T2-weighted images showed moderate-to-high signal intensity with focal bands of low signal intensity in the small nodules. The patient underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histopathological findings of the small nodules showed densely concentrated endometrial stromal cells reminiscent of a proliferative phase endometrium with a concentric arrangement of small spiral arteriole-like vessels. The small nodules exhibited an expansile growth pattern and were surrounded by less densely concentrated endometrial stromal cells intermingled with the normal uterine myometrium. LG-ESS with smooth muscle differentiation and sex cord-like elements was partially observed. In summary, LG-ESS demonstrating a unique nodule-in-nodule appearance on preoperative imaging histopathologically comprised tumor cells of varying densities. Our current case suggests that preoperative diagnostic imaging with MRI may be useful. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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