Accuracy of diagnostic imaging modalities for peripheral post-traumatic osteomyelitis
| Jazyk: | angličtina |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
CT scan
LIMITATIONS PROSTHETIC JOINT INFECTION Open reduction and internal fixation (ORIF) POSITRON EMISSION TOMOGRAPHY Osteosynthetic material LONG BONES IMPLANT-ASSOCIATED INFECTION MUSCULOSKELETAL INFECTIONS Post-traumatic osteomyelitis Ostheosynthesis Fracture PET Diagnostic imaging SCINTIGRAPHY RADIONUCLIDE FDG-PET Fracture related infection Antigranulocyte antibody scintigraphy White blood cell scintigraphy METAANALYSIS MRI |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging. 44(8):1393-1407 |
| ISSN: | 1619-7089 1619-7070 |
| DOI: | 10.1007/s00259-017-3683-7 |
| Popis: | Post-traumatic osteomyelitis (PTO) is difficult to diagnose and there is no consensus on the best imaging strategy. The aim of this study is to present a systematic review of the recent literature on diagnostic imaging of PTO.A literature search of the EMBASE and PubMed databases of the last 16 years (2000-2016) was performed. Studies that evaluated the accuracy of magnetic resonance imaging (MRI), three-phase bone scintigraphy (TPBS), white blood cell (WBC) or antigranulocyte antibody (AGA) scintigraphy, fluorodeoxyglucose positron emission tomography (FDG-PET) and plain computed tomography (CT) in diagnosing PTO were considered for inclusion. The review was conducted using the PRISMA statement and QUADAS-2 criteria.The literature search identified 3358 original records, of which 10 articles could be included in this review. Four of these studies had a comparative design which made it possible to report the results of, in total, 17 patient series. WBC (or AGA) scintigraphy and FDG-PET exhibit good accuracy for diagnosing PTO (sensitivity ranged from 50-100%, specificity ranged from 40-97% versus 83-100% and 51%-100%, respectively). The accuracy of both modalities improved when a hybrid imaging technique (SPECT/CT & FDG-PET/CT) was performed. For FDG-PET/CT, sensitivity ranged between 86 and 94% and specificity between 76 and 100%. For WBC scintigraphy + SPECT/CT, this is 100% and 89-97%, respectively.Based on the best available evidence of the last 16 years, both WBC (or AGA) scintigraphy combined with SPECT/CT or FDG-PET combined with CT have the best diagnostic accuracy for diagnosing peripheral PTO. |
| Databáze: | OpenAIRE |
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