PROGNOSTIC FACTORS IN METASTATIC NONSEMINOMATOUS GERM-CELL TUMORS - AN INTERIM ANALYSIS OF THE EORTC GU-GROUP EXPERIENCE

Jazyk:	angličtina
Rok vydání:	1993
Předmět:	CISPLATIN GERM CELL TUMORS PROGNOSTIC FACTORS VINBLASTINE NONSEMINOMATOUS TESTICULAR CANCER CHEMOTHERAPY BLEOMYCIN MULTIVARIATE-ANALYSIS TUMORS
Zdroj:	European Urology. 23(1):202-206
ISSN:	1873-7560 0302-2838
Popis:	Univariate and multivariate analyses were performed in 632 patients treated with cisplatin combination chemotherapy for metastatic non-seminomatous testicular germ cell tumours. Multivariately, the most important poor prognosis factors for the prediction of survival were: HCG greater-than-or-equal-to 10,000 IU/l, lung metastases greater-than-or-equal-to 10, abdominal metastases with a horizontal diameter of greater-than-or-equal-to 5 cm and the presence of supraclavicular metastases. If patients had 2 or more of these factors the death rates increased from 30% for patients with 2 factors to 65% for patients with 3 or 4 factors. The patients studied here are not a random sample of the metastatic testicular cancer patients in general, as the population studied comprised a large proportion of low volume metastatic disease patients. Therefore, the final analysis will include patients from all the recently completed trials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dris___01423::490a0a1cb5d14b91fd8dcc7111dd2737 https://research.rug.nl/en/publications/816bd998-0037-4519-90c7-9a54aaa96d69 Zobrazit plný text záznamu