| Autor: |
Dharampal AS, Papadopoulou SL, Meijboom WB, Weustink A, Dijkshoorn M, Nieman K, Boersma EH, de Feijter PJ, Krestin GP, ROSSI, ALEXIA |
| Přispěvatelé: |
Dharampal, A, Papadopoulou, Sl, Rossi, Alexia, Meijboom, Wb, Weustink, A, Dijkshoorn, M, Nieman, K, Boersma, Eh, de Feijter, Pj, Krestin, Gp |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
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| Popis: |
OBJECTIVES: To determine the diagnostic performance of CT coronary angiography (CTCA) in detecting and excluding left main (LM) and/or three-vessel CAD ("high-risk" CAD) in symptomatic patients and to compare its discriminatory value with the Duke risk score and calcium score. MATERIALS AND METHODS: Between 2004 and 2011, a total of 1,159 symptomatic patients (61 ± 11 years, 31 % women) with stable angina, without prior revascularisation underwent both invasive coronary angiography (ICA) and CTCA. All patients gave written informed consent for the additional CTCA. High-risk CAD was defined as LM and/or three-vessel obstructive CAD (≥50 % diameter stenosis). RESULTS: A total of 197 (17 %) patients had high-risk CAD as determined by ICA. The sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratios of CTCA were 95 % (95 % CI 91-97 %), 83 % (80-85 %), 53 % (48-58 %), 99 % (98-99 %), 5.47 and 0.06, respectively. CTCA provided incremental value (AUC 0.90, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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