Management of familial benign chronic pemphigus

Autor: Falto-Aizpurua, Leyre, Arora,Harleen, Bray,Fleta, Cervantes,Jessica
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Clinical, Cosmetic and Investigational Dermatology.
ISSN: 1178-7015
Popis: Harleen Arora,Fleta N Bray,Jessica Cervantes,Leyre A Falto Aizpurua Department of Dermatology and Cutaneous Surgery, University of Miami-Miller School of Medicine, Miami, FL, USA Abstract: Benign familial chronic pemphigus or Hailey–Hailey disease is caused by an ­autosomal dominant mutation in the ATP2C1 gene leading to suprabasilar acantholysis. The disease most commonly affects intertriginous areas symmetrically. The chronic nature of thedisease and multiple recurrences make the disease bothersome for patients and a treatment challengefor physicians. Treatments include topical and/or systemic agents and surgery including laser. This review summarizes the available treatment options. Keywords: familial benign chronic pemphigus, corticosteroids, dermabrasion, Hailey–Hailey disease, laser
Databáze: OpenAIRE
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