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Obiageli Uzoamaka Onyemelukwe,1 Albert Imhoagene Oyati,1 Solomon Sulei Danbauchi,2 Austine Obasohan3 1Department of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria; 2Department of Medicine, Jos University Teaching Hospital, Jos-Plateau State, Nigeria; 3Department of Medicine, University of Benin Teaching Hospital, Benin, Edo State, NigeriaCorrespondence: Obiageli Uzoamaka OnyemelukweDepartment of Medicine, Ahmadu Bello University Teaching Hospital, Zaria, NigeriaTel +234 8187351600Email obiageliuo629@gmail.comBackground: The study aimed at determining the response of BNP and tissue Doppler (TD) E/e´ to standard heart failure (HF) therapy in an African black population as data on these are lacking in Africa. BNP assessment in relation to HF severity and its association with its predictors were also determined.Methods: It was a longitudinal-analytical study with a one month follow-up among 100 HF patients seen at Ahmadu Bello University Teaching Hospital, Zaria-Nigeria. Two-way Repeated Measures ANOVA determined BNP levels before and after treatment according to the HF severity. Wilcoxon-Signed Ranks test determined the difference in BNP and TD E/e´ before and after treatment. Pearson’s correlation assessed log-transformed BNP’s association with its predictors.Results: BNP significantly (p |
