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Preyanit Takkinsatian,1 Dara Mairiang,2 Sasipa Sangkanjanavanich,3,4 Chirawat Chiewchalermsri,5 Athiwat Tripipitsiriwat,6 Mongkhon Sompornrattanaphan7 1Department of Pediatrics, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand; 2Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 3Division of Allergy, Immunology, and Rheumatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 4Department of Medicine, Phyathai 2 International Hospital, Bangkok, Thailand; 5Department of Medicine, Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University, Nonthaburi, Thailand; 6Division of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; 7Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Mongkhon Sompornrattanaphan, Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand, Tel/Fax +66 2419 8263, Email mongkhon.som@mahidol.ac.thAbstract: Asthma is a complex disease, caused by a combination of genetic and environmental factors. The prevalence of asthma is increasing too rapidly to be attributable to genetic factors alone. Thus, environmental factors are becoming increasingly recognized as the cause of asthma. Modifying these environmental factors may be a simple approach for asthma prevention. To date, dietary intervention is an interesting modifiable factor because it can be implemented at the population level. The modification of systemic inflammation, oxidation, and microbial composition might be a mechanistic basis for prevention. This review summarizes the mechanistic basis and evidence from clinical studies on the association between dietary factors and asthma development. We also summarize the recommendations from many organizations and regional guidelines to assist the practicing physician to improve patient care.Keywords: allergy prevention, asthma, breastfeeding, nutrition, probiotics, vitamin C, vitamin D, zinc |
