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Jamal Al Saleh,1 Hani Almoallim,2 Bassel Elzorkany,3 Ali Al Belooshi,4 Omar Batouk,5 Mohamed Fathy,6 Nora Vainstein,7 Abdullah M Kaki8 1Department of Rheumatology, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates; 2Department of Medicine, Medical College, Umm Al-Qura University, Makkah, Saudi Arabia; 3Rheumatology Department, Cairo University, Cairo, Egypt; 4Mediclinic City Hospital, Department of Surgery, UAE University, Dubai, United Arab Emirates; 5King Saud bin Abdulaziz University for Health Sciences, National Guard Health Affairs, Jeddah, Saudi Arabia; 6Pfizer, Dubai, United Arab Emirates; 7Pfizer, Buenos Aires, Argentina; 8Department of Anesthesia and Critical Care, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Abdullah M Kaki, MD, FRCPC, Professor of Anesthesiology and Pain Medicine, Faculty of Medicine, King Abdulaziz University, PO Box 2907, Jeddah, 21461, Saudi Arabia, Tel/Fax +966126408335, Email akaki@kau.edu.sa; amkaki@yahoo.comIntroduction/Objectives: This rapid evidence assessment (REA) was conducted to assess the burden of weight-bearing joint osteoarthritis in the developing countries of Africa and the Middle East.Methods: Our REA methodology used a standardized search strategy to identify observational studies, published between January 1, 2010, and April 23, 2020, reporting on outcomes pertaining to the epidemiology and humanistic or economic burden of weight-bearing osteoarthritis. Relevant data from the included studies were used for qualitative analysis.Results: Among the 20 publications reporting on knee osteoarthritis in 10 countries in Africa and the Middle East, 2 also reported on hip, and 1 on foot osteoarthritis. Prevalence of symptomatic/radiographic knee OA was 9â 14% among rheumatology outpatients and 31â 34% among those with mixed etiology osteoarthritis. Prevalence of knee OA diagnosed by magnetic resonance imaging was 70% among patients ⥠40 years of age attending a hospital in Saudi Arabia. Quality-of-life outcomes were reported in 16 publications and suggested a substantial humanistic burden of osteoarthritis, including worse pain, function, and quality of life, and more depression; comparisons between studies were hampered by the variety of tools and scoring scales used, however. No studies reported on economic outcomes.Conclusion: This REA indicates a substantial burden of osteoarthritis in weight-bearing joints in Africa and the Middle East, consistent with publications from other regions of the world.Keywords: Africa, burden of disease, Middle East, osteoarthritis, quality of life |
