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Valentin Chioncel,1,* Catalina Liliana Andrei,1,* Radu Brezeanu,1,* Crina Sinescu,1,* Anamaria Avram,1,* Alin Laurentiu Tatu2,* 1Department of Cardio-Thoracic Pathology, Faculty of Medicine, âCarol Davilaâ University of Medicine and Pharmacy, Bucharest, 050474, Romania; 2Medical and Pharmaceutical Research Unit/Competitive, Interdisciplinary Research Integrated Platform âDunărea de Josâ, ReForm-UDJG, Research Centre in the Field of Medical and Pharmaceutical Sciences, Faculty of Medicine and Pharmacy, Clinical Medical Department, âDunărea de Josâ University of Galati, Galati, 800010, Romania*These authors contributed equally to this workCorrespondence: Valentin ChioncelDepartment of Cardio-Thoracic Pathology, Faculty of Medicine, âCarol Davilaâ University of Medicine and Pharmacy, Bucharest, 050474, RomaniaEmail chioncelv@yahoo.comAbstract: The development of coronary stents has represented a revolution in the treatment of coronary heart disease. Beyond their many advantages, stents also have their limitations and complications. Allergic reactions to coronary stents are more common than acknowledged. These stented patients are exposed to foreign substances inserted in direct contact with the coronary intima. Hypersensitivity to stent components and drugs prescribed after stent insertion together with any environmental exposure seem to contribute to these adverse reactions. Patients can present to the hospital with a wide range of symptoms and multiple complications, the most important ones being instent restenosis and stent thrombosis. Although not very common (and not always easy to identify), allergic reactions after coronary or peripheral stents should be taken into account. Careful selection of patients (for elective stent implantation) depending on the propensity to allergies, although hard to achieve, represents a key factor in reducing the number of these complications.Keywords: stents, allergy, restenosis, thrombosis, Kounis syndrome |
