Elucidating the role of N-terminal phosphorylation in regulating the structure and the aggregation propensities of Huntingtin exon 1 using a semisynthetic strategy
| Autor: | Ansaloni, Annalisa |
|---|---|
| Přispěvatelé: | Lashuel, Hilal |
| Jazyk: | angličtina |
| Předmět: |
Nuclear Magnetic Resonance (NMR)
phosphorylation Circular Dichroism (CD) aggregation Post Translational Modifications (PTMs) Atomic Force Microscopy (AFM) Huntingtin exon1 (Httex1) N-terminal 17 domain (Nt17) Huntington’s disease (HD) Solid-Phase Peptide Synthesis (SPPS) Expressed Protein Ligation (EPL) Native Chemical Ligation (NCL) oligomers protein semisynthesis Transmission Electron Microscopy (TEM) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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