THE SERUM TYROSINE LEVEL AS AN INDEX OF THYROID FUNCTION
| Autor: | C. J. Miras, B. Malamos, D. A. Koutras, J. N. Karli-Samouilidou |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
medicine.medical_specialty
Goiter endocrine system diseases Endocrinology Diabetes and Metabolism Ascorbic Acid Thyroid Function Tests Hyperthyroidism Thyroid function tests Endocrinology Hypothyroidism Internal medicine Humans Medicine Tyrosine Serum tyrosine level Aged medicine.diagnostic_test business.industry Thyroid Ascorbic acid medicine.disease medicine.anatomical_structure Ascorbic Acid Deficiency Female Thyroid function business |
| Zdroj: | Journal of Endocrinology. 35:223-228 |
| ISSN: | 1479-6805 0022-0795 |
| DOI: | 10.1677/joe.0.0350223 |
| Popis: | SUMMARY Serum tyrosine was measured in 22 normal subjects, 17 patients with non-toxic goitre, ten patients with hypothyroidism, 37 patients with thyrotoxicosis and eight geriatric patients. Low values were obtained in hypothyroidism and high values in thyrotoxicosis. In thyrotoxicosis there was only a small overlap with the euthyroid subjects. Thus, measurements of serum tyrosine appear to be a useful test for the diagnosis of hyperthyroidism, not invalidated by previous iodine administration and not involving the use of radio-isotopes. Administration of vitamin C reduced the increased values of tyrosine in thyrotoxicosis to normal levels. It is suggested that a latent vitamin C deficiency may partly explain the increase in the serum tyrosine values in thyrotoxicosis. |
| Databáze: | OpenAIRE |
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