EEG activation by neuropsychological tasks in idiopathic generalized epilepsy of adolescence
| Autor: | Giedrė Gelžinienė, Giedrė Jurkevičienė, Milda Endzinienė |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Aging Adolescent Video Recording Electroencephalography Audiology Neuropsychological Tests Idiopathic generalized epilepsy Epilepsy Mental Processes stomatognathic system Developmental Neuroscience Hyperventilation medicine Humans Family history Psychiatry Sex Characteristics medicine.diagnostic_test business.industry Neuropsychology Brain Cognition General Medicine medicine.disease Sleep deprivation Pediatrics Perinatology and Child Health Sleep Deprivation Epilepsy Generalized Female Neurology (clinical) medicine.symptom business Sleep Photic Stimulation Follow-Up Studies |
| Zdroj: | Braindevelopment. 37(4) |
| ISSN: | 1872-7131 |
| Popis: | The aim of the study To evaluate the effects of neuropsychological activation (NPA) tasks on epileptiform discharges in adolescents with idiopathic generalized epilepsy (IGE) and their possible relationship to clinical epilepsy-related factors, also to compare the effects of the NPA to the habitual methods of electroencephalographic (EEG) activation. Methods/subjects Fifty-nine patients with IGE aged 14–17 years underwent baseline video-EEG recording with habitual activation procedures followed by NPA tasks, and sleep EEG after sleep deprivation on the next day. Results At least one task of NPA showed provocative effect in 18.6% of cases. There was no difference between the provocative effects of action-programming and thinking NPA task groups as well as among individual NPA tasks. The provocative effects of NPA tasks were more prevalent in photosensitive cases, especially the tasks of action-programming type ( p = 0.04). The provocative NPA effects showed no relationship to gender, age, age at seizure onset, duration of epilepsy, treatment status, presence of myoclonias, recent generalized tonic–clonic seizures, family history of epilepsy. The provocative effects of NPA were comparable to those of hyperventilation (23.7%) and intermittent light stimulation (30.5%) ( p > 0.05). Conclusions Although the provocative effects NPA tasks on epileptiform discharges on EEG did not outweigh the effects of the habitual activation procedures, NPA activation might be helpful as an additional diagnostic tool in adolescents with IGE in selected cases when routine EEG is not informative enough or when sleep EEG is readily unavailable, also in photosensitive cases. It may also help in providing advice for patients on safety issues. |
| Databáze: | OpenAIRE |
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