Specific Inhibition of Insoluble Glucan Synthase (GTF-I) by Maillard Reaction Products from Casein and Albumins
| Autor: | Kenji Koga, Hayashida Osamu, Yasuhiro Hasegawa, Yamaji Nakano, Shunsuke Kobayashi |
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| Rok vydání: | 1990 |
| Předmět: |
chemistry.chemical_classification
Glycolaldehyde biology Albumin Human serum albumin General Biochemistry Genetics and Molecular Biology stomatognathic diseases Maillard reaction symbols.namesake chemistry.chemical_compound Enzyme stomatognathic system Biochemistry chemistry Glyceraldehyde Casein symbols medicine biology.protein Bovine serum albumin General Agricultural and Biological Sciences medicine.drug |
| Zdroj: | Agricultural and Biological Chemistry. 54:1417-1424 |
| ISSN: | 0002-1369 |
| DOI: | 10.1080/00021369.1990.10870148 |
| Popis: | The Maillard reaction was done with several proteins and aldoses (glucose, glyceraldehyde, and glycolaldehyde) under both neutral and alkaline conditions. Maillard reaction products (MRP) from αs-casein and albumins (ovalbumin, bovine serum albumin, human serum albumin, and α-lactalbumin) inhibited adhesive insoluble glucan synthesis by glueosyltransferase (GTF) of Streptococcus mutans. The magnitude of the inhibitory activity in MRP from αs-casein and the three aldoses correlated with the reactivity of the aldoses with proteins. The MRP from αs-casein and albumins inhibited GTF-I and did not affect GTF-S, while their original proteins stimulated GTF-I specifically. These results suggest that the inhibitory activity of these MRP may be related to the GTF-I stimulating property of their original proteins. |
| Databáze: | OpenAIRE |
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