Bactericidal activity in the pig roundwormAscaris suum

Autor: L.M.G. Forsyth, D.W.T. Crompton, Alastair C. Wardlaw
Rok vydání: 1994
Předmět:
Zdroj: Journal of Applied Bacteriology. 76:36-41
ISSN: 0021-8847
DOI: 10.1111/j.1365-2672.1994.tb04412.x
Popis: A potent, humoral, bactericidal activity against Micrococcus luteus was discovered in pseudocoelomic fluid of the pig roundworm, Ascaris suum. The activity, which was not bacteriolytic, was not due to lysozyme or to a dietary antibiotic. It was not inactivated by exposure to 100 degrees C, to low or high pH, or to ethanol. Dialysis, electrophoresis and agar-diffusion experiments suggested that the main antibacterial activity in the fluid was associated with a basic substance of molecular weight somewhat less than 14,000 Da. Two other Gram-positive organisms, Bacillus megaterium and Staphylococcus aureus, were also killed by the Ascaris fluid, but the Gram-negative Escherichia coli, Proteus vulgaris and Bordetella bronchiseptica were insensitive.
Databáze: OpenAIRE