Changes in the concentration of ions during senescence of the human erythrocyte
| Autor: | W. Elaine Hardman, Gary D. Fullerton, Attila Miseta, Nancy K. R. Smith, Ivan L. Cameron |
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| Rok vydání: | 1993 |
| Předmět: |
Senescence
Erythrocytes Sodium Potassium chemistry.chemical_element Calcium Microanalysis Chlorides medicine Humans Magnesium Dehydration Ions Phosphorus Cell Biology General Medicine Erythrocyte Aging medicine.disease Red blood cell medicine.anatomical_structure Biochemistry chemistry Biophysics Regression Analysis Sulfur Electron Probe Microanalysis |
| Zdroj: | Cell biology international. 17(1) |
| ISSN: | 1065-6995 |
| Popis: | Flash frozen samples of normal human blood were cryosectioned and cryodried for electron probe x-ray microanalysis of the concentration of ions and elements in individual erythrocytes (RBCs). The data (expressed in mM/kg dry weight) demonstrated a systematic pattern of variation between the concentration of ions and elements in the RBCs. Specifically as K+ and Cl- decreased in concentration, Ca2+ and sulfur increased in concentration. Phosphorous, Na+ and Mg2+ did not demonstrate a significant pattern of change. These findings are related to the dehydration and to the volume decrease that accompanies senescence of the RBC. |
| Databáze: | OpenAIRE |
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