Evaluation of Whether Kidney Paired Donations Improve Overall Transplant Center Performance
| Autor: | Naoru Koizumi, Jorge Ortiz, Mehdi Nayebpour, Alexandra J Wenig |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Databases Factual Waiting Lists Kidney Paired Donation Economic shortage Unos optn Risk Assessment Donor Selection Risk Factors Internal medicine Living Donors medicine Humans Transplantation Kidney Small volume business.industry Donor selection Kidney Transplantation United States Histocompatibility Treatment Outcome surgical procedures operative medicine.anatomical_structure Donation Kidney Failure Chronic business Program Evaluation |
| Zdroj: | Experimental and Clinical Transplantation. 18:164-168 |
| ISSN: | 2146-8427 1304-0855 |
| Popis: | Increasing living-donor kidney transplant procedures via kidney paired donations could help combat organ shortages. We examined whether a higher volume of kidney paired donation transplants would lead to increased center performance.Kidney paired donation, living-donor, and deceased-donor transplant data from 165 centers between 2012 and 2016 were obtained from the UNOS OPTN database. The fixed-effects model was used for panel analysis based on Durbin-Wu-Hausman tests (P.001). Regression analyses tested associations between total transplant number and kidney paired donation-to-living donor kidney transplant ratio, incorporating up to 2-year lag terms. Regression analyses also tested associations between number of new wait list registrations and kidney paired donation transplant ratio.Mean and median number of kidney paired donor transplants equaled 3.59 and 1.2, respectively. Only 5 centers performed20 paired donation transplants annually. Mean and median ratios of paired donation transplants were 0.54 and 0.11. Total transplant number was not associated with paired donation transplant ratio of the same year (b= -.425, P = .662) or with that of 2 prior years (P = .830 and P = .629, respectively). Similarly, new wait list registrations were not correlated with paired donation transplant ratio of the same year (P= .501, P = .851) or that of 2 prior years (P = .792 and P = .816, respectively). When transplant centers were divided into those performing ≥ 10 paired donation trans-plants annually (18 transplant center, n = 90) versus those performing10 annually (147 transplant center, n = 735), no significant effects were shown (P.10).Kidney paired donation transplant does not appear to affect transplant center performance. This may be due to the small volume of these transplants currently performed by centers, thereby limiting overall growth in the number of transplants and new registrations. |
| Databáze: | OpenAIRE |
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