Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome
| Autor: | Christos Konstantinidis, Theodosios Theodosopoulos, Ioannis Vassiliou, Athanasios Marinis, Georgios Anastasopoulos, Georgios P. Fragulidis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
CREST Syndrome
Male Pathology medicine.medical_specialty medicine.medical_treatment lcsh:Surgery Case Report Adenocarcinoma Gastroenterology lcsh:RC254-282 Pancreaticoduodenectomy Duodenal Neoplasms Calcinosis Internal medicine medicine Humans Esophagus business.industry Sclerodactyly lcsh:RD1-811 Middle Aged medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens digestive system diseases medicine.anatomical_structure Oncology Duodenum Crest Surgery medicine.symptom business |
| Zdroj: | World Journal of Surgical Oncology, Vol 6, Iss 1, p 106 (2008) World Journal of Surgical Oncology |
| ISSN: | 1477-7819 |
| Popis: | Background CREST (Calcinosis, Raynaud's phenomenon, Esophageal dysmotility, Sclerodactyly and Telangiectasias) syndrome has been rarely associated with other malignancies (lung, esophagus).This is the first report of a primary adenocarcinoma of the third portion of the duodenum in a patient with CREST syndrome. Case presentation A 54-year-old male patient with CREST syndrome presented with colicky postprandial pain of the upper abdomen, diminished food uptake and a 6-Kg-body weight loss during the previous 2 months. An ulcerative lesion in the third portion of the duodenum was revealed during duodenoscopy, with a diagnosis of adenocarcinoma on biopsy specimen histology. The patient underwent a partial pancreatoduodenectomy. No adjuvant therapy was instituted and follow-up is negative for local recurrence or metastases 21 months postoperatively. Conclusion CREST syndrome has been associated with colon cancer, gastric polyps, familial adenomatous polyposis (FAP) syndrome and Crohn's disease; however, this is the first report of a primary adenocarcinoma of the duodenum in a patient with CREST syndrome. However, any etiologic relationship remains to be further investigated. |
| Databáze: | OpenAIRE |
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