[Approach to the Treatment of Atrial Fibrillation in Patients with Cardiovascular Risk Profile: Multicentric International Study]
| Autor: | Bratislav Kircanski, Velibor Jovanovic, Goran Milasinovic, G Nikcevic, Nikola N. Radovanović, Sinisa U. Pavlovic, Srdjan Raspopovic, Mirjana Živković |
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| Rok vydání: | 2016 |
| Předmět: |
cardiovascular risk factors
Adult Male medicine.medical_specialty Population Slovenia lcsh:Medicine Amiodarone Propafenone Severity of Illness Index Risk Factors Internal medicine Atrial Fibrillation medicine Prevalence Humans Sinus rhythm education Aged First episode education.field_of_study treatment business.industry lcsh:R Sotalol Atrial fibrillation General Medicine Middle Aged medicine.disease Comorbidity Cross-Sectional Studies Cardiology Female business Anti-Arrhythmia Agents Serbia medicine.drug |
| Zdroj: | Srpski Arhiv za Celokupno Lekarstvo, Vol 143, Iss 9-10, Pp 551-558 (2015) |
| ISSN: | 0370-8179 |
| Popis: | Introduction. Atrial fibrillation (AF), the most common arrhythmia that requires treatment, does not come out of the focus of researchers. Monitoring its prevalence and effects of therapy is a good guideline approach to the growing population of patients in which this arrhythmia occurs. Objective. The aim of the study was to evaluate the efficacy of treatment of AF and cardiovascular profiles in the observed population. Methods. In this observational, cross-sectional, multicenter, international study, 584 patients in 30 centers in Serbia and Slovenia, older than 18 years and with AF or in sinus rhythm with a history of AF, were included. The assessment of the efficacy of treatment of AF was performed by analyzing the frequency of adequate therapeutic effect of medication in rhythm or frequency control in patients with AF. Results. The results confirmed that the highest incidence of AF duration is more than seven days, and is accompanied by symptoms. Inadequate frequency regulation was registered at 8.9% of patients. Hypertension was registered in two-thirds of all patients, while other cardiovascular risk factors were registered in about one-third of patients. An echocardiographic finding in the group of patients with AF confirms generally adequate left ventricular function with a slightly enlarged left atrium (4.6±0.8 cm). Increasing age and time from the first episode of AF decreases the probability of maintaining sinus rhythm, while symptomatic AF had a positive impact on the presence of sinus rhythm. Propafenone, sotalol and amiodarone showed a statistically significant connection with a positive therapeutic response, while β-blockers had a negative impact on the probability of establishing and maintaining sinus rhythm. Conclusion. Characteristics of therapeutic approaches, risks, comorbidity of patient populations in Slovenia and Serbia correspond to the fullest extent with the recommendations for good clinical practice, which further stresses the need for extensive measures in these regions. |
| Databáze: | OpenAIRE |
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