What are the Risk Factors for Renal Failure following Open Elective Abdominal Aortic Aneurysm Repair?
| Autor: | D. Purkayastha, Charles McCollum, Antony D. Grayson, Stuart W Grant, M.J. Grant |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Kidney failure Cohort Studies chemistry.chemical_compound Aortic aneurysm Blood Vessel Prosthesis Implantation Postoperative Complications Risk Factors Elective surgical procedure medicine Humans Prospective Studies Renal Insufficiency Prospective cohort study Aged Retrospective Studies Medicine(all) Creatinine business.industry Age Factors Retrospective cohort study medicine.disease Abdominal aortic aneurysm Surgery chemistry England Female Cardiology and Cardiovascular Medicine Complication Elective Surgical Procedure business Abdominal surgery Aortic Aneurysm Abdominal |
| Zdroj: | European Journal of Vascular and Endovascular Surgery. 43(2):182-187 |
| ISSN: | 1078-5884 |
| DOI: | 10.1016/j.ejvs.2011.11.018 |
| Popis: | Objectives Renal failure following abdominal aortic aneurysm (AAA) repair is a common and significant complication. The objective of this study was to identify risk factors for renal failure following open elective AAA repair. Design A retrospective analysis of prospectively collected multi-centre data. Materials Consecutive data on patients undergoing open elective AAA repair were collected between January 2000 and December 2010. Patients with pre-operative serum creatinine >200 μmol/L were excluded. Methods Renal failure was reported by clinicians and included all patients requiring post-operative renal-replacement therapy. Univariate and multivariate analyses were used to identify renal failure risk factors. A simplified clinical risk score was developed. Results Post-operative renal failure occurred in 140 (6.0%) of 2347 patients and was associated with age >75 (OR = 1.58, 95%CI 1.11–2.26), symptomatic AAA (OR = 1.77, 95%CI 1.24–2.52), supra/juxta renal AAA (OR = 2.17, 95%CI 1.32–3.57) pre-operative serum creatinine >150 (OR = 2.75, 95%CI 1.69–4.50), treated hypertension (OR = 1.87, 95%CI 1.28–2.74), and respiratory disease (OR = 2.08, 95%CI 1.45–2.97). Patients with post-operative renal failure had significantly higher 30-day mortality (35.0% vs. 4.3%, p Conclusions Renal failure following open elective AAA repair was associated with an increased risk of mortality. Risk factors for post-operative renal failure were identified and a simple clinical risk score developed to facilitate focussed care strategies for high-risk patients. |
| Databáze: | OpenAIRE |
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