Neuroendocrine cells are present in the domestic fowl ovary
| Autor: | Armida Báez Saldaña, Teresa Fortoul van der Goes, Pablo G. Hofmann, Gabriel Gutiérrez Ospina, Margarita González del Pliego |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Histology Fowl Synaptophysin Fluorescent Antibody Technique Ovary Ovarian Medulla chemistry.chemical_compound Neuroendocrine Cells Neurofilament Proteins Internal medicine medicine Animals Tyrosine Molecular Biology Ecology Evolution Behavior and Systematics Neuroendocrine cell biology Chromogranin A Cell Biology Original Articles biology.organism_classification medicine.anatomical_structure Endocrinology Indolamines chemistry biology.protein Female Anatomy Chickens Biomarkers Developmental Biology |
| Zdroj: | Journal of anatomy. 222(2) |
| ISSN: | 1469-7580 |
| Popis: | Neuroendocrine cells are present in virtually all organs of the vertebrate body; however, it is yet uncertain whether they exist in the ovaries. Previous reports of ovarian neurons and neuron-like cells in mammals and birds might have resulted from misidentification. The aim of the present work was to determine the identity of neuron-like cells in immature ovaries of the domestic fowl. Cells immunoreactive to neurofilaments, synaptophysin, and chromogranin-A, with small, dense-core secretory granules, were consistently observed throughout the sub-cortical ovarian medulla and cortical interfollicular stroma. These cells also displayed immunoreactivity for tyrosine, tryptophan and dopamine β-hydroxylases, as well as to aromatic L-DOPA decarboxylase, implying their ability to synthesize both catecholamines and indolamines. Our results support the argument that the ovarian cells previously reported as neuron-like in birds, are neuroendocrine cells. |
| Databáze: | OpenAIRE |
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