Hepatic Silicone Granulomas Secondary to Ruptured Breast Implants: A Report of Two Cases
| Autor: | Billie Fyfe, Rachel Hudacko, Ronald E. Gordon, Vinod K. Rustgi, Carolyn Catalano, Kapil Anand, Henry J. Katz, Francisco Zaldana, Tina John |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Elevated liver enzymes Case Report Granulomatous inflammation 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Silicone Medicine In patient lcsh:RC799-869 medicine.diagnostic_test business.industry General Medicine Elevated alkaline phosphatase 030104 developmental biology chemistry Liver biopsy Etiology lcsh:Diseases of the digestive system. Gastroenterology medicine.symptom Differential diagnosis business |
| Zdroj: | Case Reports in Hepatology Case Reports in Hepatology, Vol 2019 (2019) |
| ISSN: | 2090-6595 2090-6587 |
| Popis: | The differential diagnosis of hepatic granulomas is vast and includes infections, drugs, immunologic diseases, foreign material exposure, and neoplasia. Silicone, whether directly injected into tissues or used as a filler in breast implants, is known to cause localized granulomatous reactions. It can also migrate to other anatomic locations resulting in granulomatous inflammation at a distance. We report two cases of unsuspected hepatic silicone granulomas in patients undergoing liver biopsy for isolated elevated alkaline phosphatase levels, both with a history of ruptured breast implants. These cases highlight the need for awareness of hepatic silicone granulomas as an etiology of elevated liver enzymes in patients with a history of surgical interventions utilizing silica, such as cosmetic surgery. |
| Databáze: | OpenAIRE |
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