When might hemispheric favouring of epileptiform discharges begin?
| Autor: | E. Simon, Michelle D. Holmes, Carl B. Dodrill, Russell P. Saneto, J. W. Miller, Donald F. Farrell, N. F. Watson, J.D Kuratani, Michael J. Doherty, M.S De Menezes |
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| Rok vydání: | 2003 |
| Předmět: |
Telencephalon
Adolescent Clinical Neurology Context (language use) Electroencephalography Lateralization of brain function Epilepsy medicine Humans Ictal Child Retrospective Studies Chi-Square Distribution medicine.diagnostic_test Age Factors Infant Newborn Infant General Medicine medicine.disease nervous system diseases nervous system Neurology Child Preschool Neurology (clinical) Psychology Neuroscience |
| Zdroj: | Seizure. 12:595-598 |
| ISSN: | 1059-1311 |
| DOI: | 10.1016/s1059-1311(03)00107-9 |
| Popis: | Purpose: EEG studies based on adult populations report interictal epileptiform discharges (EDS) favour the left hemisphere. It is not clear when favouring becomes apparent as similar paediatric studies have not been performed. Methods: The authors reviewed 1579 paediatric EEG interpretations for evidence of hemispheric favouring of focal epileptiform discharges. Analysis focused on first-time EEG results. Results: Right hemispheric favouring of interictal epileptiform discharges occurs in childhood, it remits around 5 years of age whereupon left-sided favouring occurs more frequently ( P =0.004, Fisher's Exact). Conclusion: Hemispheric vulnerabilities to interictal focal epileptiform activity may display discrete age-related favouring. These findings are discussed in context of normal hemispheric maturation. |
| Databáze: | OpenAIRE |
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