Evaluation of therapy management and outcome in Takotsubo syndrome
| Autor: | Witali Pomjanski, Nadine Abanador-Kamper, Lars Kamper, Melchior Seyfarth, Anamaria Wolf-Pütz, Judith Wolfertz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome lcsh:Diseases of the circulatory (Cardiovascular) system 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Interquartile range Internal medicine Antithrombotic medicine Humans 030212 general & internal medicine Heart Failure Cardiovascular magnetic resonance imaging Ejection fraction business.industry Antiplatelet therapy Retrospective cohort study medicine.disease Prognosis Magnetic Resonance Imaging Antithrombotic management lcsh:RC666-701 Heart failure Cardiovascular agent Cardiology Takotsubo cardiomyopathy Cardiology and Cardiovascular Medicine business Mace Research Article |
| Zdroj: | BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-9 (2017) BMC Cardiovascular Disorders |
| ISSN: | 1471-2261 |
| DOI: | 10.1186/s12872-017-0661-8 |
| Popis: | Background To date there is no validated evidence for standardized treatment of patients with Takotsubo syndrome (TTS). Medication therapy after final TTS diagnosis remains unclear. Previous data on patient outcome is ambivalent. Aim of this study was to evaluate medication therapy in TTS and to analyze patient outcome. Methods Within an observational retrospective cohort study we analyzed our medical records and included 72 patients with TTS that underwent cardiovascular magnetic resonance imaging (CMR) after a median of 2 days interquartile range (IQR 1–3.5). We investigated medication therapy at discharge. Medication implementation and major adverse clinical events (MACE) were prospectively evaluated after a median follow-up of 24 months (IQR 6–43). Left ventricular function, myocardial oedema and late gadolinium enhancement were analyzed in a CMR follow-up if available. Results Antithrombotic therapy was recommended in 69 (96%) patients including different combinations. Antiplatelet monotherapy was prescribed in 28 (39%) patients. Dual antiplatelet therapy was recommended in 29 (40%) patients. Length of therapy duration varied from one to twelve months. Only in one case oral anticoagulation was prescribed due to apical ballooning with a left ventricular ejection fraction |
| Databáze: | OpenAIRE |
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