Impact of lifestyle-related diseases on carotid arterial wall elasticity as evaluated by an ultrasonic phased-tracking method in Japanese subjects
| Autor: | Hideyuki Hasegawa, Makoto Kato, Toshio Yamagishi, Yoshiro Koiwa, Hiroshi Kanai |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Japan Risk Factors Internal medicine Diabetes mellitus Internal Medicine Medicine Humans cardiovascular diseases Elasticity (economics) Elastic modulus Life Style Ultrasonography Metabolic Syndrome business.industry Biochemistry (medical) Middle Aged medicine.disease Atherosclerosis Elasticity Blood pressure Carotid Arteries Intima-media thickness cardiovascular system Cardiology Ultrasonic sensor Female Metabolic syndrome Cardiology and Cardiovascular Medicine business Tunica Intima Tunica Media Dyslipidemia |
| Zdroj: | Journal of atherosclerosis and thrombosis. 16(6) |
| ISSN: | 1880-3873 |
| Popis: | Aim: We investigated the relationship between coronary risk factors and the intima-media thickness (IMT) and wall elasticity of carotid arteries. A new real-time ultrasonic measurement system that allows measurement of the elasticity of the carotid arterial intima-media complex was applied to 350 subjects, who were also checked for the presence/absence of hypertension, dyslipidemia, diabetes mellitus and regular smoking. Simultaneous measurement of the elastic modulus and IMT was conducted at four sites in the bilateral carotid arteries. Methods and Results: In the group with maximum IMT (max IMT) ＜1.1 mm, the IMT, as well as the mean elastic modulus in the circumferential direction (Eθ), showed positive correlations with age and coronary risk factors. Multiple regression analysis showed that age, systolic blood pressure and pulse rate remained independent determinants of Eθ. The number of criteria fulfilling the diagnosis of metabolic syndrome showed a good positive correlation with the value of Eθ in the group with max IMT values ＜1.1 mm. Conclusion: Measurement of carotid arterial wall elasticity together with IMT is useful to detect distortions in intramural elasticity distribution occurring in the early stages of atherosclerosis. J Atheroscler Thromb, 2009; 16:782-791. |
| Databáze: | OpenAIRE |
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