Muscular Polyarteritis Nodosa
| Autor: | Nam Soon Cho, Dong Hwee Kim, Eul Sik Yoon, Seong Jae Choi, Hyun Soo Choi, Seung Nam Yang |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.drug_class Biopsy Muscular Diseases Rheumatology Musculoskeletal Pain Azathioprine medicine Humans Arteritis Muscle Skeletal Gait Glucocorticoids Soleus muscle Leg medicine.diagnostic_test Electromyography Polyarteritis nodosa business.industry Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Polyarteritis Nodosa Surgery Prednisone Corticosteroid Drug Therapy Combination Differential diagnosis Range of motion business Vasculitis Immunosuppressive Agents Follow-Up Studies |
| Zdroj: | JCR: Journal of Clinical Rheumatology. 18:249-252 |
| ISSN: | 1076-1608 |
| DOI: | 10.1097/rhu.0b013e318262e3dd |
| Popis: | We present an unusual case of a 26-year-old man with muscular polyarteritis nodosa (PAN) with severe calf pain and gait disturbance. Magnetic resonance imaging of the lower limbs demonstrated highly increased signal intensity in both soleus muscles and the lateral head of the left gastrocnemius muscle. Biopsies of the soleus muscle showed acute necrotizing arteritis. The calf pain and limited range of motion of ankle dorsiflexion subsided from day 1 on administration of oral corticosteroid at high dosage and were completely resolved by 4 months. After tapering corticosteroid to 10 mg, symptoms recurred. A combined regimen of immunosuppressants was found to maintain symptomatic relief.Muscular PAN should be included in the differential diagnosis of a patient presenting with symptoms of acute or subacute calf pain. Although this muscular PAN was so far been benign, complete remission of the underlying process may be difficult to achieve. |
| Databáze: | OpenAIRE |
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