Evaluating dose regimens of apomorphine, an open-label study
| Autor: | Apichat Kongkanand, J Opanuraks, N Choeypunt, Anupan Tantiwong, T Amornvejsukit, Kavirach Tantiwongse |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Apomorphine Urology medicine.medical_treatment Dopamine agonist Medical Records Erectile Dysfunction Epidemiology medicine Humans Chemotherapy business.industry Middle Aged medicine.disease Thailand Sexual desire Erectile dysfunction Tolerability Patient Satisfaction Anesthesia Concomitant Dopamine Agonists business medicine.drug |
| Zdroj: | International journal of impotence research. 15 |
| ISSN: | 0955-9930 |
| Popis: | The aim of the study was to investigate the safety and efficacy of apomorphine SL (apo SL) 2 and 3 mg, using a dose-optimisation regime in 110 Asian men with erectile dysfunction (ED) during a 10-week open-label study. Based on daily diaries kept by each patient, 63% showed an improvement in their sexual life. Patient responses to the International Index for Erection Function 15 questionnaires showed that there was an improvement in erectile function from baseline score after treatment with apo SL (from 15.9 to 20.4), and intercourse satisfaction (from 7.7 to 9.9), as well as slight improvements in orgasmic function (from 6.8 to 7.5) and total satisfaction (from 41.9 to 50.8). There was no marked improvement seen in sexual desire. In conclusion, apo SL is safe and efficacious in the treatment of ED in this patient population, irrespective of underlying diseases and concomitant medications. |
| Databáze: | OpenAIRE |
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