| Autor: |
Niyaz, Ahmad, Ahmed A, Albassam, Mohd, Faiyaz Khan, Zabih, Ullah, Taysser, Mohammed Buheazah, Hussain, Salman AlHomoud, Hassan, Ali Al-Nasif |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Saudi Journal of Biological Sciences. 29:3704-3716 |
| ISSN: |
1319-562X |
| DOI: |
10.1016/j.sjbs.2022.02.017 |
| Popis: |
5-Fluorouracil (5-FU) is a drug of choice for colorectal-cancer. But oral therapeutic efficacy of 5-FU is restricted due to their very little bioavailability because of poor membrane permeability and GIT-absorption. We have developed a multiple nanoemulsion (w/o/w i.e. 5-FU-MNE) in which 5-FU incorporated to improve their oral-absorption. Globule-size of opt-5-FU-MNE was 51.64 ± 2.61 nm with PDI and ZP 0.101 ± 0.001 and -5.59 ± 0.94, respectively. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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