Quantification of cutaneous allergic reactions using 3D optical imaging: A feasibility study
| Autor: | Matthijs C. M. Grimbergen, Mark D. den Blanken, Thomas Rustemeyer, Niels Liberton, Mark B.M. Hofman, Ruud Verdaasdonk, Sebastiaan A. S. van der Bent |
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| Přispěvatelé: | Dermatology, AII - Inflammatory diseases, Radiology and nuclear medicine, ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Biomedical Photonic Imaging, Health Technology Implementation |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
skin
3d printed Allergic reaction elevation UT-Hybrid-D lichenoid Dermatology allergic reaction red 01 natural sciences Imaging phantom Dermatitis Atopic 3D scanner 010309 optics Lesion 030207 dermatology & venereal diseases 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Optical imaging 0103 physical sciences Humans Medicine volume Tattooing Phantoms Imaging business.industry Optical Imaging Trilinear interpolation Original Articles optical scanner phantom Optical scanning Feasibility Studies Original Article medicine.symptom business Nuclear medicine tattoo ink Interpolation |
| Zdroj: | den Blanken, M D, van der Bent, S, Liberton, N, Grimbergen, M, Hofman, M B M, Verdaasdonk, R & Rustemeyer, T 2020, ' Quantification of cutaneous allergic reactions using 3D optical imaging: A feasibility study ', Skin Research and Technology, vol. 26, no. 1, pp. 67-75 . https://doi.org/10.1111/srt.12765 Skin research and technology, 26(1), 67-75. Wiley-Blackwell Skin Research and Technology, 26(1), 67-75. Wiley-Blackwell Skin Research and Technology |
| ISSN: | 0909-752X |
| DOI: | 10.1111/srt.12765 |
| Popis: | Background User‐independent quantitative measures of cutaneous allergic reactions can help the physicians manage and evaluate the treatment of cutaneous allergic reactions. In this paper, we present and validate a method to quantify the elevation, volume and area of cutaneous allergic reactions to red tattoos. Methods The skin surface of allergic tattoo reactions was imaged using an optical 3D scanner. The in‐house developed analysis tool measured the elevation, volume and area of the lesions, compared to a reference surface. This reference surface was created by 3D interpolation of the skin after manual removal of the lesions. The error of the interpolation tool was validated using a digital arm model. The error of our optical scanner was determined using a 3D printed lesion phantom. The clinical feasibility of the method was tested in 83 lesions in 17 patients. Results The method showed clear potential to assess skin elevation, volume change and area of an allergic reaction. The validation measurements revealed that the error due to interpolation increases for larger interpolation areas and largely determined the error in the clinical measurements. Lesions with a width ≥4 mm and an elevation ≥0.4 mm could be measured with an error below 26%. Patient measurements showed that lesions up to 600 mm2 could be measured accurately, and elevation and volume changes could be assessed at follow‐up. Conclusion Quantification of cutaneous allergic reactions to red tattoos using 3D optical scanning is feasible and may objectify skin elevation and improve management of the allergic reaction. |
| Databáze: | OpenAIRE |
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