Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
| Autor: | Zilton A. Andrade, Rosella de Oliveira Santos, Aryon de Almeida Barbosa Junior |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1992 |
| Předmět: |
Male
Microbiology (medical) Pathology medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Intestinal schistosomiasis lcsh:RC955-962 Liver Diseases Parasitic lcsh:QR1-502 Schistosomiasis Intestinal fibrosis Biology lcsh:Microbiology Mice Fibrosis hemic and lymphatic diseases schistosomiasis medicine intestinal fibrosis Animals General pattern Intestinal Diseases Parasitic Collagen degradation medicine.disease Schistosomiasis mansoni Resorption Intestines Liver Curative treatment Female periovular granuloma |
| Zdroj: | Memórias do Instituto Oswaldo Cruz, Volume: 87, Issue: 1, Pages: 25-31, Published: MAR 1992 Memórias do Instituto Oswaldo Cruz., Vol 87, Iss 1, Pp 25-31 (1992) |
| Popis: | A histological, morphometric and immunocytochemical study of schistosomal periovular granulomas in the liver and intestines of mice revealed that intestinal granulomas are smaller and contain less collagen than those in the liver. After curative treatment intestinal granulomas undergo a relatively more rapid resorption, although the general pattern of collagen degradation apparently does not differ from that observed in the liver. Tendency to form scattered, usually isolated granulomas that are only mildly fibrogenic, coupled with a well-balanced process of resorption appear as the explanation why intestinal fibrosis is not an outstanding feature of schistosomiasis as it is in the liver. |
| Databáze: | OpenAIRE |
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