No evidence of automatic atrial overdrive pacing efficacy on reduction of paroxysmal atrial fibrillation
| Autor: | Dia El Allaf, Philip De Vusser, Dirk Stockman, Hung-Fat Tse, Georges H. Mairesse, Rob van Mechelen, Norbert M. van Hemel, Jüri Voitk, Indrek Roose, Sinikka Yli-Mäyry, Arjan van den Bos, Chu-Pak Lau, Juhani Koistinen, Willem G. de Voogt |
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| Rok vydání: | 2007 |
| Předmět: |
Tachycardia
Male medicine.medical_specialty Pacemaker Artificial Paroxysmal atrial fibrillation Cardiology law.invention Sick sinus syndrome Randomized controlled trial law Physiology (medical) Internal medicine Atrial Fibrillation Medicine Humans Tachycardia Paroxysmal Aged Proarrhythmia Cross-Over Studies business.industry Cardiac Pacing Artificial Atrial fibrillation Middle Aged medicine.disease Atrial Function Crossover study Atrial Lead Treatment Outcome Anesthesia Female medicine.symptom Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents Algorithms |
| Zdroj: | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 9(9) |
| ISSN: | 1099-5129 |
| Popis: | Aims Paroxysmal atrial fibrillation (PAF) is frequently encountered in pacemaker patients, most commonly in sick sinus syndrome. The combination of site-specific pacing in conjunction with an overdrive algorithm combined with antiarrhythmic drugs on the incidence of PAF in patients with a conventional indication for pacing is unknown. Methods and results Patients with pacemaker indication and PAF received a DDDR-pacemaker, which included an automatic atrial overdrive (AO) algorithm. The atrial lead was implanted in either the right atrial appendage (RAA) ( n = 83) or the right low-atrial septum (LAS) ( n = 94). The algorithm was switched on or off in a 3 month, single blind crossover design and antiarrhythmic drugs were kept stable. A control group of 96 patients (LAS, n = 14; RAA, n = 84) without PAF served as controls to assess any proarrhythmic effect of overdrive pacing. Atrial fibrillation (AF) burden defined as cumulative time in mode switch was not reduced during automatic AO from either the RAA or from the LAS. The reduction was not effective both for AF of short ( |
| Databáze: | OpenAIRE |
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