Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome treated with a combination of isotretinoin and pamidronate
| Autor: | Emad Sultan, Suraj S. Venna, Ross Zeltser, Alyssa G. Bishop, Hassan Galadari, Daihung Do |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Hyperostosis Pamidronate Dermatology Acneiform eruption Skin Diseases Acneiform Eruptions Synovitis medicine Humans Psoriasis Isotretinoin Acne Osteitis Diphosphonates business.industry Pamidronic acid Syndrome Middle Aged medicine.disease Pustulosis Drug Therapy Combination medicine.symptom business medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 61(1) |
| ISSN: | 1097-6787 |
| Popis: | Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a clinically heterogeneous entity, encompassing a variety of debilitating conditions that have in common inflammation of the skeletal system and skin. To date, there is a paucity of documented efficacious treatment options. We report a 48-year-old man with skeletal and cutaneous signs and symptoms who improved dramatically after treatment with a combination of isotretinoin and pamidronate. This report provides an alternative treatment regimen for SAPHO that addresses the possible underlying pathophysiology of this likely underdiagnosed syndrome. |
| Databáze: | OpenAIRE |
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