Iron-Dependent Synthesis of Hemolysins by Staphylococcus aureus

Autor:	V. V. Leonov, T. Kh. Timokhina, V. V. Varnitsina, N. A. Kurlovich, V. V. Kosterina
Rok vydání:	2012
Předmět:	inorganic chemicals Staphylococcus aureus Chemistry Iron fungi Hemolysin General Medicine medicine.disease_cause Hemolysis General Biochemistry Genetics and Molecular Biology Microbiology Hemolysin Proteins medicine Humans In patient Staphylococcus aureus delta toxin Cells Cultured
Zdroj:	Bulletin of Experimental Biology and Medicine. 153:41-43
ISSN:	1573-8221 0007-4888
DOI:	10.1007/s10517-012-1645-4
Popis:	We studied the effect of Fe(2+) on hemolysin synthesis by Staphylococcus aureus. Hemolytic activity of staphylococci was shown to be iron-dependent. Addition of Fe(2+) to the nutrient medium induced the synthesis of α-hemolysin by staphylococci. Increasing the concentration of Fe(2+) was followed by an increase in hemolytic activity of staphylococci. Inducible synthesis of α-hemolysin probably serves as an important pathogenetic factor in the development of staphylococcal infection in patients with excessive iron accumulation in the body.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff995d66f083ceb23ea43515fc15febb https://doi.org/10.1007/s10517-012-1645-4 Zobrazit plný text záznamu Full text from SpringerLink