A Mixed Outbreak of Epidemic Typhus Fever and Trench Fever in a Youth Rehabilitation Center: Risk Factors for Illness from a Case-Control Study, Rwanda, 2012
| Autor: | Jared Omolo, Samuel Rwunganira, Marie Aimee Muhimpundu, Eric Jon Tongren, Thierry Nyatanyi, Wangeci Gatei, Agnes Binagwaho, Edward J Mills, Jennifer H. McQuiston, Robert F. Massung, Tura Galgalo, Pratima L Raghunathan, Jean Baptiste Koama, Francois Habiyaremye, Jean Marie Uwimana, Kimberly Boer, Katherine A. Muldoon, Irenee Umulisa, Anicet G. Dahourou, J Condo |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult Male Pediatrics medicine.medical_specialty Adolescent 030106 microbiology Population Attack rate Rehabilitation Centers Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Bartonella quintana Risk Factors Virology Case fatality rate Phthiraptera Odds Ratio Medicine Animals Humans 030212 general & internal medicine Rickettsia prowazekii education education.field_of_study business.industry Coinfection Incidence (epidemiology) Incidence Rwanda Outbreak Odds ratio Articles medicine.disease Survival Analysis Trench fever Trench Fever Surgery Infectious Diseases Case-Control Studies Parasitology business Typhus Typhus Epidemic Louse-Borne |
| Zdroj: | The American journal of tropical medicine and hygiene. 95(2) |
| ISSN: | 1476-1645 |
| Popis: | In August 2012, laboratory tests confirmed a mixed outbreak of epidemic typhus fever and trench fever in a male youth rehabilitation center in western Rwanda. Seventy-six suspected cases and 118 controls were enrolled into an unmatched case-control study to identify risk factors for symptomatic illness during the outbreak. A suspected case was fever or history of fever, from April 2012, in a resident of the rehabilitation center. In total, 199 suspected cases from a population of 1,910 male youth (attack rate = 10.4%) with seven deaths (case fatality rate = 3.5%) were reported. After multivariate analysis, history of seeing lice in clothing (adjusted odds ratio [aOR] = 2.6, 95% confidence interval [CI] = 1.1-5.8), delayed (≥ 2 days) washing of clothing (aOR = 4.0, 95% CI = 1.6-9.6), and delayed (≥ 1 month) washing of beddings (aOR = 4.6, 95% CI = 2.0-11) were associated with illness, whereas having stayed in the rehabilitation camp for ≥ 6 months was protective (aOR = 0.20, 95% CI = 0.10-0.40). Stronger surveillance and improvements in hygiene could prevent future outbreaks. |
| Databáze: | OpenAIRE |
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