Liver and biliary damages following transarterial chemoembolization of hepatocellular carcinoma: comparison between drug-eluting beads and lipiodol emulsion
| Autor: | Arnaud Monier, Serge Aho, Alban Denys, Vincent Dunet, Pierre Deltenre, Pierre Bize, Rafael Duran, Boris Guiu |
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| Rok vydání: | 2016 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Bile Duct Diseases Gastroenterology 030218 nuclear medicine & medical imaging 03 medical and health sciences Ethiodized Oil 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Chemoembolization Therapeutic Aged Retrospective Studies Venous Thrombosis Chemotherapy medicine.diagnostic_test business.industry Liver Diseases Incidence (epidemiology) Liver Neoplasms Magnetic resonance imaging Interventional radiology Retrospective cohort study General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Liver 030220 oncology & carcinogenesis Hepatocellular carcinoma Toxicity Lipiodol Female Bile Ducts Radiology business medicine.drug |
| Zdroj: | European Radiology. 27:1431-1439 |
| ISSN: | 1432-1084 0938-7994 |
| Popis: | To compare transarterial chemoembolization (TACE)-related hepatic toxicities of conventional TACE (cTACE) and drug-eluting beads TACE (DEB-TACE) in patients with intermediate-stage hepatocellular carcinoma. In this retrospective study, 151 consecutive patients undergoing cTACE or DEB-TACE and MRI 3-6 weeks before and after therapy were included. Toxicity was assessed on imaging (global hepatic damages (GHD), overall biliary injuries, biliary cast, bile duct dilatation, intrahepatic biloma, portal thrombosis), and clinico-biological follow-ups. Tumour response, time to progression (TTP), and overall survival were assessed. Factors influencing complication rate were identified by generalized equation logistic regression model. Biliary injuries and intrahepatic biloma incidence were significantly higher following DEB-TACE (p |
| Databáze: | OpenAIRE |
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