Partial splenic embolization in patients with idiopathic portal hypertension
| Autor: | Angela Giojelli, Maurizio Romano, Marco Salvatore, Domenico Pomponi, Gaetano Capuano |
|---|---|
| Přispěvatelé: | Romano, M, Giojelli, A, Capuano, G, Pomponi, D, Salvatore, Marco |
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Population embolization interventional Splenic artery Esophageal and Gastric Varices medicine.artery Hypertension Portal medicine Humans Radiology Nuclear Medicine and imaging Embolization education CIRRHOSIS education.field_of_study Varix Esophageal disease business.industry VEIN portal hypertension General Medicine medicine.disease CHRONIC PERSISTENT HEPATITIS Embolization Therapeutic Thrombocytopenia radiology Surgery therapeutic THROMBOSIS Treatment Outcome HEMODYNAMICS Splenomegaly Portal hypertension Female Splenic disease business Varices Gastrointestinal Hemorrhage Tomography Spiral Computed Spleen Follow-Up Studies |
| Zdroj: | European journal of radiology 49 (2004): 268–273. doi:10.1016/S0720-048X(03)00134-7 info:cnr-pdr/source/autori:Romano, M.; Salvatore, M.; Pomponi, D.; Capuano, G.; Giojelli, A/titolo:Partial splenic embolization in patients with idiopathic portal hypertension/doi:10.1016%2FS0720-048X(03)00134-7/rivista:European journal of radiology/anno:2004/pagina_da:268/pagina_a:273/intervallo_pagine:268–273/volume:49 |
| Popis: | Purpose: To evaluate the effectiveness of partial splenic embolization (PSE) in patients with idiopathic portal hypertension (IPH) in reducing variceal bleeding episodes, splenomegaly and thrombocytopenia. Materials and methods: Six patients (2M, 417, mean age 30.3 years) with IPH presenting with splenomegaly, thrombocytopenia and recurrent variceal bleeding were treated with PSE using gelatin sponge (four patients) or Contour particles (two patients) as embolization material. Results: PSE was performed successfully in all cases; 3F coaxial microcatheters were necessary in two patients due to extreme splenic artery tortuosity. The average amount of devascularized parenchyma at CT I week after PSE was 71%. Splenomegaly and thrombocytopenia improved in all cases, with a mean platelet count increase of 120000/mm(3) and an average 68% reduction of spleen volume at follow up. Variceal bleeding did not recur after PSE. Esophageal or gastroesophageal varices disappeared (one patient) or significantly reduced (five patients) at endoscopic controls. No significant complications were noted. The follow up was of at least 18 months in all patients; mean follow up was 28.2 months. Conclusion: In patients with IPH PSE can be effective in preventing variceal bleedings, in reducing spleen volume and in significantly increasing platelet count; therapeutic results were durable in our population. (C) 2003 Elsevier Ireland Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|