Surgical treatment in refractory epilepsy: seizure outcome results based on invasive EEG monitorization
| Autor: | Aydin Aydoseli, Nermin Gorkem Sirin, Betül Tekin Güveli, Altay Sencer, Yavuz Aras, Sibel Velioglu, Zahide Mail Gurkan, Ulger Aydogan Culha, Akin Sabanci, Aysen Gokyigit, Ali Canbolat, Candan Gürses, Nerses Bebek, Fulya Eren, Bülent Kara, Günay Gül, Betül Baykan |
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| Přispěvatelé: | Gürses, Rabia Candan (ORCID 0000-0002-3752-1825 & YÖK ID 110149), Mail Gürkan, Zahide, Şirin, Nermin Görkem, Kara, Bülent, Gül, Günay, Şengül Eren, Fulya, Tekin Güveli, Betül, Velioğlu, Sibel, Sabancı, Akin, Aydoseli, Aydın, Aras, Yavuz, Bebek, Nerses, Baykan, Betül, Sencer, Altay, Canbolat, Ali Tuncay, Gökyigit, Ayşen, Aydoğan Culha, Ülger, School of Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Male Drug Resistant Epilepsy Pediatrics medicine.medical_specialty Clinical neurology Surgery Epilepsy Seizures medicine Humans Epilepsy surgery Retrospective Studies Hippocampal sclerosis business.industry Refractory epilepsy Invasive EEG monitoring Outcome Eloquent cortex Electroencephalography Retrospective cohort study Sequela Cortical dysplasia medicine.disease Engel classification Magnetic Resonance Imaging Treatment Outcome Etiology Female Neurology (clinical) business |
| Zdroj: | Turkish Neurosurgery |
| Popis: | Aim: to discuss seizure outcomes of patients with invasive electroencephalography (EEG) monitorization (IEM) following their epilepsy surgery at our centre. Material and Methods: forty-seven patients suffering from refractory epilepsy and who were evaluated by invasive EEG were included in this retrospective study at Istanbul Faculty of Medicine from 2003 to 2017. We examined the Video EEG and invasive EEG monitorization, cranial MRI, SPECT, PET and neuropsychological tests of all patients. Postoperative seizure outcome results were evaluated according to Engel classification. The factors affecting seizure outcomes were discussed. Results: twenty-six of the patients were female (55.3%), 21 were male (44.7). The average age was 32.0 (+/- 12.4). Forty-three patients had surgery and the average age of these patients was 26,6 (+/- 11.15). 38.3% of the patients had hippocampal sclerosis (HS), 23.4% had focal cortical dysplasia (FCD), 8.5% had a tumor, 14.9% had sequela lesion and 14.9% had unknown etiology. Postoperative seizure status according to the Engel classification showed that 81.6% of the patients were class I, 10.5% were class II, 2.6% were class III and 5.3% were class IV. Conclusion: a significant relation was statistically determined between structural MRI lesion and favorable seizure outcome (p0.05). We argue that IEM is an essential examination for favorable outcomes for determining the epileptogenic zone and/or the proximity of the functional structures. NA |
| Databáze: | OpenAIRE |
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