Tracer clearance in radionuclide cisternography in patients with spontaneous intracranial hypotension
| Autor: | Hiroaki Ikegawa, T Takahashi, A Watanabe, Takako Umeda, Toru Horikoshi, M Uchida |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Radioisotope Dilution Technique Thoracic spine Metabolic Clearance Rate Intracranial Hypotension Octreotide Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid medicine Spontaneous Intracranial Hypotension Humans In patient 030212 general & internal medicine Radionuclide Imaging Myelography Epidural blood patch Radionuclide medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging General Medicine Middle Aged Pentetic Acid Subdural Effusion Female Neurology (clinical) Radiopharmaceuticals Nuclear medicine business Tracer Clearance 030217 neurology & neurosurgery |
| Zdroj: | Cephalalgia : an international journal of headache. 26(8) |
| ISSN: | 0333-1024 |
| Popis: | We semiquantitatively analysed radionuclide cisternography in three patients with spontaneous cerebrospinal fluid (CSF) leakage diagnosed by typical symptoms and magnetic resonance imaging findings before and several months after treatment with epidural blood patch. Radioactivity in the whole CSF space was measured immediately after and at 1, 5, 7 and 24 h after intrathecal injection of 111In-diethylenetriaminepentaacetic acid (DTPA). Initial findings included the vague appearance of leakage in the thoracic spine in two patients, early bladder filling at 1 h in one and a lack of tracer filling into the high cranial convexity in all three. The radioactivity count rapidly decreased within several hours after injection and reached 20± of the initial value at 24 h. In contrast, no rapid decrease was observed after treatment and more than 50± of tracer remained at 24 h after injection. Semiquantitative analysis of tracer clearance may provide additional information in the diagnosis of CSF leakage, especially with no obvious qualitative findings. |
| Databáze: | OpenAIRE |
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