Morphological and functional aspects of experimental gentamicin nephrotoxicity in young beagles and foals
| Autor: | Edward J. Hinsman, Jim E. Riviere, Coppoc Gl, Traver Ds, William W. Carlton |
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| Rok vydání: | 1983 |
| Předmět: |
Kidney
Pathology medicine.medical_specialty General Veterinary business.industry animal diseases Aminoglycoside Physiology Toxic nephropathy General Medicine Nephrotoxicity medicine.anatomical_structure Dogs medicine Animals Gentamicin Kidney Diseases Horses Gentamicins business medicine.drug Subclinical infection |
| Zdroj: | Veterinary research communications. 7(1-4) |
| ISSN: | 0165-7380 |
| Popis: | A toxic nephropathy induced by gentamicin was investigated in young beagles and foals. Preliminary results indicated that a single 15 mg/kg dose of gentamicin administered to beagles produced subclinical functional and morphological changes in the kidney. Light histological lesions of aminoglycoside nephrotoxicosis were detected in all foals given gentamicin, suggesting an enhanced susceptibility of young horses to clinical renal dysfunction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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