ADAMTS13 activity and inhibitor

Autor:	Vandita Johari, Jonathan K. Freeman, Clandine Habib, Carlos Acevedo-Gadea, Adriana Doldan-Silvero
Rok vydání:	2008
Předmět:	medicine.medical_specialty Heterozygote Thrombotic thrombocytopenic purpura ADAMTS13 Protein Enzyme-Linked Immunosorbent Assay Genes Recessive Gastroenterology Adamts13 activity Sensitivity and Specificity Substrate Specificity hemic and lymphatic diseases Internal medicine von Willebrand Factor medicine Fluorescence Resonance Energy Transfer Humans Enzyme Inhibitors Prospective cohort study Horseradish Peroxidase Metalloproteinase Hematology Plasma Exchange Purpura Thrombotic Thrombocytopenic business.industry Homozygote Retrospective cohort study Reference Standards medicine.disease ADAMTS13 Recombinant Proteins Protein Structure Tertiary Molecular Weight Purpura ADAM Proteins Immunology Mutation medicine.symptom business
Zdroj:	American journal of hematology. 83(10)
ISSN:	1096-8652
Popis:	Thrombotic thrombocytopenic purpura (TTP) is often associated with acquired or congenital deficiency of the von Willebrand factor-cleaving metalloprotease, ADMATS13 (Lammle B et al., J Thromb Haemost 2005;3:1663-1675; Schneppenheim et al., Blood 2003;101:1845-1850). Although undetectable levels of enzyme activity (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7a928479019d33cbcd5640a45e8465 https://pubmed.ncbi.nlm.nih.gov/18756543 Zobrazit plný text záznamu Plný text