Bioprospecting of endophytes in medicinal plants of Thar Desert: An attractive resource for biopharmaceuticals
| Autor: | Mukesh Meena, Garima Yadav |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
ISM Indian summer monsoon Resource (biology) PDA Potato dextrose agar Bioactive molecules Review Endomicrobial diversity 01 natural sciences Applied Microbiology and Biotechnology 03 medical and health sciences EtOAc Ethyl acetate Medicinal plants 010608 biotechnology Endophytes MIC Minimum inhibitory concentration 030304 developmental biology 0303 health sciences Bioprospecting Vegetation biology Traditional medicine Host (biology) fungi food and beverages DDW Double distilled water biology.organism_classification Antimicrobial ITS Internal transcribed spacer CF Colonization frequency Biopotential Phoma SCA Starch casein agar TP248.13-248.65 Calotropis gigantea Biotechnology |
| Zdroj: | Biotechnology Reports, Vol 30, Iss, Pp e00629-(2021) Biotechnology Reports |
| ISSN: | 2215-017X |
| DOI: | 10.1016/j.btre.2021.e00629 |
| Popis: | Highlights • Endophytes act as chemical synthesizers of the secondary metabolites of the host plant. • Endophytic microflora has been isolated from a wide array of plants. • It can serve as a good alternative source for pharmaceutically important compounds. • The arid ecosystem of Thar Desert is a rich repository of ethnomedicinal plants. • Role of endophytes in the synthesis of bioactive molecules used to enhance production. Endophytes live asymptomatically within the healthy tissues of plant parts of the host, has grabbed the attention of ecologists, chemists, and researchers to have a broad spectral of biotechnological potential. It has been proven that almost all plants harbor endophytes within themselves. Numerous studies indicated that endophytes act as chemical synthesizers of the secondary metabolites of their host plant. Various medicinal plants of the Thar Desert have been used by the local folks of the Rajasthan to treat several diseases ailments for time immemorial. On the basis of their prior knowledge of ethnopharmacological usage of medicinally important plants of Thar Desert, several researchers directed their studies in search of endophytic microflora of such medicinally important plants for the discovery of novel bioactive molecules of pharmaceutical importance, for instance, taxol producing endophytic fungus Phoma sp. isolated from Calotropis gigantea as well as Aspergillus fumigatus, an endophytic fungus reported from Moringa oleifera demonstrated an effective antibiofilm, antimicrobial and antiproliferative activity. This review sheds light on the endophytic microflora of the ethnomedicinal plants of the Thar Desert and their biopotential as a promising source of pharmaceutically important naturally derived compounds. |
| Databáze: | OpenAIRE |
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