BRAFV600E mutation in oral melanocytic nevus and oral mucosal melanoma

Autor: Bruno Augusto Benevenuto de Andrade, Ricardo Santiago Gomez, Taynara Asevedo Campos de Resende, Carolina Cavaliéri Gomes, Oslei Paes de Almeida, Wilson Delgado-Azañero, Adalberto Mosqueda-Taylor, Bruna Pizziolo Coura, Vanessa Fátima Bernardes
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Cancer Research
Skin Neoplasms
Letter
genomic DNA
genetic association
very elderly
laser capture microdissection
Gene mutation
hard palate
pigmented nevus
purl.org/pe-repo/ocde/ford#3.02.21 [https]
middle aged
mucosal melanoma
gene mutation
Melanoma
Aged
80 and over

Nevus
Pigmented

Oral melanoma
clinical article
adult
Oral cancer
Mucosal melanoma
B Raf kinase
Middle Aged
Melanocytic nevus
cohort analysis
gingiva
aged
female
Oncology
priority journal
Mutation (genetic algorithm)
histopathology
Oral melanocytic nevi
Female
Oral Surgery
Adult
Proto-Oncogene Proteins B-raf
mutational analysis
oral mucosal melanoma
medicine.medical_specialty
Mouth cancer
Adolescent
cancer genetics
oral melanocytic nevus
Young Adult
male
medicine
Pigmented Nevus
mouth tumor
Humans
human
quality control
Aged
data analysis software
business.industry
Mouth Mucosa
medicine.disease
mouth cancer
Dermatology
DNA isolation
purl.org/pe-repo/ocde/ford#3.02.14 [https]
human tissue
allele specific real time polymerase chain reaction
stomatognathic diseases
adolescent
Mutation
buccal mucosa
Histopathology
business
Popis: Oral mucosal melanoma (OMM) is a rare and aggresive melanocytic malignant neoplasm, with incidence lower that 0.01 cases per 100.000 person-year and a worse prognosis than cutaneous melanoma. Oral melanocytic nevus (OMN) is a rare benign oral neoplasm, whose malignant transformation to OMM is debatable. The genetic basis of both lesions has been poorly explored and OMM is studied together with other mucosal melanomas as a group, despite being a separate entity....
Databáze: OpenAIRE