HIV Vaccine Trial Participation Among Ethnic Minority Communities
| Autor: | Danielle S. Seiden, Dallas Swendeman, Naihua Duan, Peter A. Newman, Svetlana Popova, Kathleen Johnston Roberts, Ellen T. Rudy |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Gerontology Health Knowledge Attitudes Practice Ethnic group Humans Medicine Pharmacology (medical) HIV vaccine Poverty Minority Groups AIDS Vaccines Clinical Trials as Topic biology business.industry virus diseases Hispanic or Latino Focus Groups biology.organism_classification Vaccine efficacy Los Angeles Focus group Black or African American Infectious Diseases Lentivirus Female Patient Participation Thematic analysis business Prejudice Qualitative research |
| Zdroj: | JAIDS Journal of Acquired Immune Deficiency Syndromes. 41:210-217 |
| ISSN: | 1525-4135 |
| DOI: | 10.1097/01.qai.0000179454.93443.60 |
| Popis: | Background Underrepresentation of ethnic minority communities limits the generalizability of HIV vaccine trial results. We explored perceived barriers and motivators regarding HIV vaccine trial participation among low-socioeconomic ethnic minority respondents at risk for HIV. Methods Six focus group interviews were conducted using a semistructured interview guide. Participants (N = 58, mean age = 36 years, 37% female, and 56% Latino/a and 35% African American) were recruited using venue-based sampling in Los Angeles. Data were analyzed using narrative thematic analysis and Ethnograph qualitative software. Results Perceived barriers to HIV vaccine trial participation, in rank order, were (1) vaccine-induced HIV infection, (2) physical side effects, (3) uncertainty about vaccine efficacy, (4) uncertainty about other vaccine characteristics, (5) mistrust, (6) low perceived HIV risk, (7) study demands, (8) stigma, and (9) vaccine-induced HIV seropositivity. Motivators were (1) protection against HIV infection, (2) free insurance and/or medical care, (3) altruism, and (4) monetary incentives. Conclusions Population-specific HIV vaccine trial recruitment and implementation strategies should address trial risks from a family perspective, cultural gender norms, mistrust, low perceived HIV risk, the importance of African-American and Latino/a community participation in HIV vaccine trials, and misconceptions about gaining protection against HIV infection. Increasing the cultural relevance of trial recruitment and implementation should facilitate the participation of Latinos/as and African Americans in HIV vaccine trials. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|