Erratum: Tong, T., et al. α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts. Molecules 2019, 24, 1804
Autor: | Wesuk Kang, Taesun Park, Youna Moon, Jinju Park, Tao Tong |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Ultraviolet Rays
Photoaging Pharmaceutical Science Ionone Models Biological Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Drug Discovery medicine Humans Physical and Theoretical Chemistry Hyaluronic Acid Organic Chemistry Dermis Fibroblasts medicine.disease Molecular biology Skin Aging Up-Regulation n/a chemistry Chemistry (miscellaneous) Molecular Medicine Collagen Erratum Norisoprenoids |
Zdroj: | Molecules Molecules, Vol 25, Iss 3517, p 3517 (2020) |
ISSN: | 1420-3049 |
Popis: | Ultraviolet (UV) light-induced wrinkle formation is a major dermatological problem and is associated with alteration in collagen. Here, we investigated the potential of α-ionone, a naturally occurring aromatic compound, in regulation of UVB-induced photoaging in human Hs68 dermal fibroblasts and identified the mechanisms involved. We found that in human dermal fibroblasts, α-ionone inhibited UVB-induced loss of collagen. α-Ionone upregulated the molecules participating in the TGF-β-SMAD pathway (TGF-β1, phospho-SMAD2/3 |
Databáze: | OpenAIRE |
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