Improved production of succinic acid from Basfia succiniciproducens growing on A. donax and process evaluation through material flow analysis
| Autor: | Giovanna Ruoppolo, Sergio D’ambrosio, Donatella Cimini, Licia Lama, Lucio Zaccariello, Chiara Schiraldi, Vincenza Faraco, Olimpia Pepe |
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| Přispěvatelé: | Cimini, Donatella, Zaccariello, Lucio, D'Ambrosio, Sergio, Lama, Licia, Ruoppolo, Giovanna, Pepe, Olimpia, Faraco, Vincenza, Schiraldi, Chiara, Cimini, D, Zaccariello, L, D'Ambrosio, S, Lama, L, Ruoppolo, G, Pepe, O, Faraco, V, Schiraldi, C |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Material flow analysi analysis lcsh:Biotechnology Biomass Basfia succiniciproducen Management Monitoring Policy and Law 01 natural sciences Applied Microbiology and Biotechnology lcsh:Fuel Arundo donax Succinic acid 03 medical and health sciences chemistry.chemical_compound Hydrolysis lcsh:TP315-360 010608 biotechnology lcsh:TP248.13-248.65 Material flow 030304 developmental biology Inhibition 2. Zero hunger 0303 health sciences biology Renewable Energy Sustainability and the Environment Material flow analysis Fed-batch biology.organism_classification Pulp and paper industry Basfia succiniciproducens General Energy Energy (all) chemistry Biofuel Yield (chemistry) Fermentation Biotechnology Pre-pilot scale |
| Zdroj: | Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-14 (2019) Biotechnology for biofuels 12 (2019). doi:10.1186/s13068-019-1362-6 info:cnr-pdr/source/autori:Cimini D., Zaccariello L., D'Ambrosio S., Lama L., Ruoppolo R., Pepe O., Faraco V., Schiraldi C./titolo:Improved production of succinic acid from Basfia succiniciproducens growing on A. donax and process evaluation through material flow analysis/doi:10.1186%2Fs13068-019-1362-6/rivista:Biotechnology for biofuels/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:12 |
| ISSN: | 1754-6834 |
| DOI: | 10.1186/s13068-019-1362-6 |
| Popis: | Background: Due to its wide range of applications in the food, pharmaceutical and chemical fields, microbial syn- thesis of succinic acid is receiving growing attention, generating already relevant industrial results, as well as fueling constant research for improvements. In order to develop a sustainable process, a special focus is now set on the exploitation and conversion of lignocellulosic biomasses into platform chemicals. Results: In the present work we used Basfia succiniciproducens BPP7 in separated hydrolysis and fermentation experi- ments with Arundo donax as starting material. Fed-batch strategies showed a maximal production of about 37 g/L of succinic acid after 43 h of growth and a productivity of 0.9 g/L h on the pilot scale. Global mass balance calculations demonstrated a hydrolysis and fermentation efficiency of about 75%. Moreover, the application of a material flow analysis showed the obtainment of 88.5 and 52 % of succinic acid, per kg of virgin biomass and on the total generated output, respectively. Conclusions: The use of fed-batch strategies for the growth of B. succiniciproducens on A. donax improved the titer and productivity of succinic acid on pre-pilot scale. Process evaluation through material flow analysis showed successful results and predicted a yield of succinic acid of about 30% in a fed-batch process that uses A. donax as only carbon source also in the feed. Preliminary considerations on the possibility to achieve an energetic valorization of the residual solid coming from the fermentation process were also carried out. Keywords: Basfia succiniciproducens, Arundo donax, Fed-batch, Succinic acid, Pre-pilot scale, Inhibition, Material flow analysis |
| Databáze: | OpenAIRE |
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