Antenatal Depression and Risk of Gestational Diabetes, Adverse Pregnancy Outcomes, and Postpartum Quality of Life

Autor: Caro Minschart, Chantal Mathieu, Kyara De Weerdt, Christophe De Block, Astrid Elegeert, Sofie Vandeginste, Yves Jacquemyn, Paul Van Crombrugge, Johan Verhaeghe, Anne Loccufier, Carolien Moyson, Hilde Verlaenen, Katrien Benhalima, Annouschka Laenen, Chris Vercammen, Roland Devlieger, Toon Maes, Els Dufraimont, Annick Van den Bruel, Katrien De Clippel, Farah Mekahli
Rok vydání: 2021
Předmět:
Zdroj: The journal of clinical endocrinology and metabolism
ISSN: 1945-7197
0021-972X
Popis: Aims To determine the impact of depressive symptoms on pregnancy outcomes and postpartum quality of life in women with gestational diabetes mellitus (GDM) and normal glucose tolerance (NGT). Methods 1843 women from a prospective cohort study received universal GDM screening with an oral glucose tolerance test (OGTT). The Center for Epidemiologic Studies–Depression questionnaire was completed before GDM diagnosis was communicated and in GDM women in early postpartum. All participants completed the 36-Item Short Form Health Survey (SF-36) health survey postpartum. Results Women who developed GDM (231; 12.5%) had significantly more often depressive symptoms than NGT (1612; 87.5%) women [21.3% (48) vs 15.1% (239), odds ratio (OR) 1.52, 95% confidence interval (CI) (1.08-2.16), P = 0.017]. Compared to GDM women without depressive symptoms, depressed GDM women attended less often the postpartum OGTT [68.7% (33) vs 87.6% (155), P = 0.002], remained more often depressed [37.1% (13) vs 12.4% (19), P Conclusions Women with antenatal symptoms of depression develop more often GDM. GDM women with depressive symptoms remain more often depressed postpartum with lower quality of life. NGT women with depressive symptoms have higher rates of labor inductions and lower quality of life postpartum compared to nondepressed NGT women.
Databáze: OpenAIRE