Biochemical responses of broiler chicks to folate deficiency
| Autor: | Rennie Js, C. C. Whitehead, J. A. Armstrong |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
Vitamin medicine.medical_specialty Erythrocytes animal structures Folate Metabolism Nutritional Status Medicine (miscellaneous) Phosphoribosyl Pyrophosphate Dihydrofolate reductase activity Folic Acid Deficiency chemistry.chemical_compound Folic Acid Bone Marrow Internal medicine Dihydrofolate reductase medicine Animals Nutrition and Dietetics biology Broiler DNA Metabolism Deoxyuridine Tetrahydrofolate Dehydrogenase medicine.anatomical_structure Endocrinology Liver chemistry biology.protein Bone marrow Chickens |
| Zdroj: | British Journal of Nutrition. 69:801-808 |
| ISSN: | 1475-2662 0007-1145 |
| DOI: | 10.1079/bjn19930080 |
| Popis: | The effects of folate sufficiency and deficiency in three pathways of folate metabolism were studied in 2- and 3-week-old broiler chicks. Erythrocyte phosphoribosylpyrophosphate concentrations and dihydro- folate reductase (EC 1.5.1.3) activity were significantly elevated in folate deficiency. Percentage incorporation of deoxyuridine into bone marrow DNA was reduced in folate deficiency. There was a trend towards reduced liver dihydrofolate reductase activity in deficient chicks. These studies identify further biochemical criteria that can be used to assess folate status of chicks. |
| Databáze: | OpenAIRE |
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