Diverting Ileostomy Duration Is the Main Determinant of Ileostomy-Related Complications after Surgical Treatment of Rectum Cancer
Autor: | Ahmet Akbaş, Onder Karabay, Erkan Yavuz, Serhat Meric, Yuksel Altinel, Nadir Adnan Hacım |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Article Subject business.industry Colorectal cancer medicine.medical_treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens Cancer Rectum Odds ratio medicine.disease Logistic regression Surgery 03 medical and health sciences Ileostomy 0302 clinical medicine medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Adjuvant therapy medicine 030211 gastroenterology & hepatology business Complication RC254-282 Research Article |
Zdroj: | Journal of Oncology Journal of Oncology, Vol 2020 (2020) |
ISSN: | 1687-8450 |
Popis: | Background. This study aimed to investigate factors associated with the development of ileostomy complications in rectal cancer patients, including those who received neoadjuvant treatment. Methods. This retrospective trial included 133 consecutive patients who underwent surgery for rectal cancer with temporary diverting ileostomy. Patients’ demographic characteristics as well as the pre- and postclosure outcomes and complications were analyzed. Results. In logistic regression analysis, longer duration of ileostomy emerged as a significant independent predictor of any complication during ileostomy. The respective odds ratios for 3–6 months and >6 months vs. p=0.023; and OR, 15.2 (95% CI, 3.1–75.2), p=0.001. An additional stepwise model also identified hypertension as a significant predictor. In stepwise logistic regression model, adjuvant chemoradiotherapy emerged as significant independent predictor of “any ileostomy-related complication after ileostomy closure”: OR, 4.5 (2.0–10.2), p<0.001. Conclusion. Duration of ileostomy appears to be the main determinant of ileostomy-related complications. Patients who had received neoadjuvant or adjuvant therapy had longer ileostomy duration, which may be attributed to the concerns of the surgeon or to the complications themselves. |
Databáze: | OpenAIRE |
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