| Autor: |
Makoto Arai, Yuka Yasuda, Akiko Kobori, H Noma, Kanako Ishizuka, Maeri Yamamoto, Norio Ozaki, Yuko Arioka, Hidenaga Yamamori, Branko Aleksic, Michio Suzuki, Shusuke Numata, Chia-Hsiang Chen, Tomoko Toyota, Chaochen Wang, Yuichiro Watanabe, Toshimichi Yamamoto, T Maeda, Teppei Shimamura, Shuji Iritani, Tomoko Shiino, Ayako Nunokawa, Maki Morikawa, Itaru Kushima, Masanari Itokawa, Ryota Hashimoto, Akira Yoshimi, Tomoko Oya-Ito, M C Cheng, Mitsuhiro Miyashita, Toshiyuki Someya, Tsutomu Takahashi, Tetsuro Ohmori, Tetsuya Iidaka, Yota Uno, Mami Yoshida, Shohko Kunimoto, Masahiro Nakatochi, Jingrui Xing, Yuto Takasaki, Yukako Nakamura, Daisuke Mori, Takashi Okada, Hiroki Kimura, Nakao Iwata, Takeo Yoshikawa, Masashi Ikeda, Y A Chuang, Shuko Hamada |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Molecular Psychiatry. 22:430-440 |
| ISSN: |
1476-5578
1359-4184 |
| Popis: |
Recent schizophrenia (SCZ) studies have reported an increased burden of de novo copy number variants (CNVs) and identified specific high-risk CNVs, although with variable phenotype expressivity. However, the pathogenesis of SCZ has not been fully elucidated. Using array comparative genomic hybridization, we performed a high-resolution genome-wide CNV analysis on a mainly (92%) Japanese population (1699 SCZ cases and 824 controls) and identified 7066 rare CNVs, 70.0% of which were small ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full text from SpringerLink 