The effect of liver transplantation on circulating levels of estradiol and progesterone in male patients: Parallelism with hepatopulmonary syndrome and systemic hyperdynamic circulation improvement
| Autor: | Boixeda D, José Luis Moya, Rafael Bárcena, Conrado M. Fernández-Rodríguez, Víctor Moreira, D.A. de Luis, S. Ávila, Rocío Aller, A. L. San Roman |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Pulmonary Circulation medicine.medical_specialty Cardiac output Endocrinology Diabetes and Metabolism Hemodynamics Gastroenterology Endocrinology Sex hormone-binding globulin Internal medicine Blood plasma medicine Humans Cardiac Output Gonadal Steroid Hormones Hepatopulmonary syndrome Progesterone Estradiol biology Pulmonary Gas Exchange business.industry Middle Aged medicine.disease Liver Transplantation Vasodilation Transplantation medicine.anatomical_structure Hyperdynamic circulation Vascular resistance biology.protein Vascular Resistance Blood Gas Analysis business Hepatopulmonary Syndrome |
| Zdroj: | Journal of Endocrinological Investigation. 24:503-509 |
| ISSN: | 1720-8386 0391-4097 |
| DOI: | 10.1007/bf03343883 |
| Popis: | The correction of hepatopulmonary syndrome (HPS) after liver transplantation (LT) remains controversial. The aims of our study were to: 1) analyze whether LT reverses HPS; 2) note any relationship between HPS and the systemic hemodynamic disturbance; and 3) note changes in circulating sex hormones and the possible association with pulmonary and systemic hemodynamic changes. Systemic hemodynamic parameters, cardiac output and systemic vascular resistance (SVR), sex hormones, and intrapulmonary vasodilatation assessed by contrast transesophageal echocardiography, and gas exchange abnormalities were investigated in 19 patients with advanced cirrhosis prior to and 6 months (176.8+/-30 days) after LT. LT was followed by a marked reduction in cardiac output (6.6+/-1.7 vs 3.5+/-0.5 l/min; p |
| Databáze: | OpenAIRE |
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