Hsr-omega, A Novel Gene Encoded by a Drosophila Heat Shock Puff

Autor:	Mary Lou Pardue, Karen L. Traverse, J C Garbe, William G. Bendena, M E Fini, N C Hogan
Rok vydání:	1990
Předmět:	Genetics Cytoplasm Transcription (biology) Heat shock protein Drosophilidae Gene expression Biology Drosophila melanogaster Nuclear protein General Agricultural and Biological Sciences biology.organism_classification Gene
Zdroj:	The Biological Bulletin. 179:77-86
ISSN:	1939-8697 0006-3185
Popis:	Although originally identified because of its abundant transcription in heat shock, the hsr-omega gene is active, at generally lower levels, in non-stressed cells. The locus produces an unusual set of three transcripts. Evidence from a variety of experiments suggests that one of these transcripts acts in the nucleus, possibly to regulate the activity of a nuclear protein. Another of the transcripts appears to act in the cytoplasm, possibly monitoring or regulating some aspect of translation. The two transcripts together could have a role in coordinating nuclear and cytoplasmic activity. A number of processes occur in eukaryotic cells in which nuclear and cytoplasmic activities need to be coordinated; we suggest that hsr-omega plays a role in such coordination.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff45572dd7cafea1833a5b872043c765 https://doi.org/10.2307/1541741 Zobrazit plný text záznamu